ACTN4 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-14759-20UL
60 ul
£183.00
E-AB-14759-60UL
120 ul
£272.00
E-AB-14759-120UL
200 ul
£420.00
E-AB-14759-200UL
About this Product
- SKU:
- E-AB-14759
- Additional Names:
- ACTN 4,ACTN4,Actinin alpha 4,Alpha-actinin-4,DKFZp686K23158,F actin cross linking protein,F-actin cross-linking protein,FSGS,FSGS 1,FSGS1,Focal segmental glomerulosclerosis 1,Non muscle alpha actinin 4,Non-muscle alpha-actinin 4,actinin 4,actinin4
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.8 mg/ml
- Extra Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human ACTN4
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-actn4_polyclonal_antibody-e_ab_14759
