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Antibodies

AANAT Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-14757-20UL
60 ul
£183.00
E-AB-14757-60UL
120 ul
£272.00
E-AB-14757-120UL
200 ul
£420.00
E-AB-14757-200UL
About this Product
SKU:
E-AB-14757
Additional Names:
AA-NAT,Aanat,Aralkylamine N-acetyltransferase,Arylalkylamine N acetyltransferase,SNAT,Serotonin N-acetyltransferase,Serotonin acetylase
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.2 mg/ml
Extra Details:
The protein encoded by this gene belongs to the acetyltransferase superfamily.It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland.Melatonin is essential for the function of the circadian clock that influences activity and sleep.This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation.This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human AANAT
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody