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Antibodies

PIM1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-14694-20UL
60 ul
£183.00
E-AB-14694-60UL
120 ul
£272.00
E-AB-14694-120UL
200 ul
£420.00
E-AB-14694-200UL
About this Product
SKU:
E-AB-14694
Additional Names:
Oncogene PIM 1,Oncogene PIM1,PIM,PIM 1,PIM1,PIM3,Pim 1 kinase,Pim 1 oncogene,Pim2,Proto oncogene serine/threonine protein kinase Pim 1,Proto-oncogene ,pim 1 kinase 44 kDa isoform,pim 1 oncogene (proviral integration site 1),pim1 kinase 44 kDa isoform
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.4 mg/ml
Extra Details:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.
Host:
Rabbit
Immunogen:
Recombinant protein of human PIM1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody