STRADB Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-14553-20UL
60 ul
£183.00
E-AB-14553-60UL
120 ul
£272.00
E-AB-14553-120UL
200 ul
£420.00
E-AB-14553-200UL
About this Product
- SKU:
- E-AB-14553
- Additional Names:
- ALS2 chromosome region gene 2,ALS2CR2,Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 2,Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein,CALS 21,CALS-21,ILP interacting protein ILPIPA,ILP-interacting prote
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.1 mg/ml
- Extra Details:
- This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human STRADB
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-stradb_polyclonal_antibody-e_ab_14553
