ALKBH2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-14464-20UL
60 ul
£183.00
E-AB-14464-60UL
120 ul
£272.00
E-AB-14464-120UL
200 ul
£420.00
E-AB-14464-200UL
About this Product
- SKU:
- E-AB-14464
- Additional Names:
- 2OG Fe(II) oxy DC1,9530023G02,ABH 2,ABH2,ALKB2,ALKBH2,ALKBH2 alkB,Alkylated DNA repair protein alkB homolog,Alkylated DNA repair protein alkB homolog 2,Alkylation repair homolog 2,Alpha ketoglutarate dependent dioxygenase ,alkB alkylation repair homolog 2
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human ALKBH2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-alkbh2_polyclonal_antibody-e_ab_14464
