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Antibodies

SH-PTP2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-14341-20UL
60 ul
£183.00
E-AB-14341-60UL
120 ul
£272.00
E-AB-14341-120UL
200 ul
£420.00
E-AB-14341-200UL
About this Product
SKU:
E-AB-14341
Additional Names:
BPTP3,CFC,JMML,METCDS,MGC14433,NS1,OTTHUMP00000166107,OTTHUMP00000166108,PTN11,Protein tyrosine phosphatase 2,Protein tyrosine phosphatase 2C,Protein tyrosine phosphatase non receptor type 11,Protein-tyrosine phosphatase 1D,Protein-tyrosine phosphatase 2C
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.3 mg/ml
Extra Details:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human PTPN11
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody