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Antibodies

MCM6 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-14210-20UL
60 ul
£183.00
E-AB-14210-60UL
120 ul
£272.00
E-AB-14210-120UL
200 ul
£420.00
E-AB-14210-200UL
About this Product
SKU:
E-AB-14210
Additional Names:
DNA replication licensing factor MCM6,MCG40308,MCM6,MCM6 minichromosome maintenance deficient 6,MCM6 minichromosome maintenance deficient 6 (MIS5 homolog,Mcm6,Minichromosome maintenance complex component 6,Minichromosome maintenance deficient (m,S. pombe)
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.8 mg/ml
Extra Details:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication.The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Host:
Rabbit
Immunogen:
Recombinant protein of human MCM6
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody