GREM1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-14111-20UL
60 ul
£183.00
E-AB-14111-60UL
120 ul
£272.00
E-AB-14111-120UL
200 ul
£420.00
E-AB-14111-200UL
About this Product
- SKU:
- E-AB-14111
- Additional Names:
- BMP antagonist 1;CKTSF1B1;Cell proliferation inducing gene 2 protein;Cell proliferation-inducing gene 2 protein;Cysteine knot superfamily 1;Cysteine knot superfamily BMP antag;colorectal adenoma and carcinoma 1
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.3 mg/ml
- Extra Details:
- This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human GREM1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-grem1_polyclonal_antibody-e_ab_14111
