FADD Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-14078-20UL
60 ul
£183.00
E-AB-14078-60UL
120 ul
£272.00
E-AB-14078-120UL
200 ul
£420.00
E-AB-14078-200UL
About this Product
- SKU:
- E-AB-14078
- Additional Names:
- FADD;FADD protein;FAS-;Fas (TNFRSF6) associated via death domain;Fas TNFRSF6 associated via death domain;Fas associated via death domain;Fas associating death domain containing protein;Fas associating protein;Fas associating protein with death domain
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human FADD
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-fadd_polyclonal_antibody-e_ab_14078
