DUSP22 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-14065-20UL
60 ul
£183.00
E-AB-14065-60UL
120 ul
£272.00
E-AB-14065-120UL
200 ul
£420.00
E-AB-14065-200UL
About this Product
- SKU:
- E-AB-14065
- Additional Names:
- DUS22,Dual specificity protein phosphatase 22,Dusp22,JNK stimulatory phosphatase 1,JNK-stimulatory phosphatase-1,JSP 1,JSP-1,JSP1,LMW DSP2,LMW-DSP2,Low molecular weight dual specificity phosphatase 2,MAP kinase phosphatase x,Mitogen activated protein kina
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human DUSP22
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-dusp22_polyclonal_antibody-e_ab_14065
