CDC27 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-13987-20UL
60 ul
£183.00
E-AB-13987-60UL
120 ul
£272.00
E-AB-13987-120UL
200 ul
£420.00
E-AB-13987-200UL
About this Product
- SKU:
- E-AB-13987
- Additional Names:
- ANAPC3,APC 3,APC3,Anaphase Promoting Complex 3,Anaphase Promoting Complex Subunit 3,Anaphase promoting complex protein 3,Anaphase-promoting complex subunit 3,CDC27,CDC27 homolog,CDC27Hs,Cdc 27,Cdc27,Cell Division Cycle 27,Cell division cycle protein 27 ho
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.3 mg/ml
- Extra Details:
- The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55 CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human CDC27
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cdc27_polyclonal_antibody-e_ab_13987
