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Antibodies

Cathepsin E Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-13974-20UL
60 ul
£183.00
E-AB-13974-60UL
120 ul
£272.00
E-AB-13974-120UL
200 ul
£420.00
E-AB-13974-200UL
About this Product
SKU:
E-AB-13974
Additional Names:
CATE,CTSE,Cathepsin E,Cathepsin E form II,Erythrocyte membrane aspartic proteinase,Slow moving proteinase
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.6 mg/ml
Extra Details:
The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human CTSE
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody