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Antibodies

Amphiphysin II Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-13951-20UL
60 ul
£183.00
E-AB-13951-60UL
120 ul
£272.00
E-AB-13951-120UL
200 ul
£420.00
E-AB-13951-200UL
About this Product
SKU:
E-AB-13951
Additional Names:
AMPH 2,AMPH2,AMPHL,Amphiphysin 2,Amphiphysin II,Amphiphysin like protein,Amphiphysin-like protein,BIN1,Bin1,Box Dependant MYC Interacting Protein 1,Box-dependent myc-interacting protein 1,Bridging integrator 1,DKFZp547F068,MGC10367,MGC105,amphiphysin-like
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.1 mg/ml
Extra Details:
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor.Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin.Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process.Studies in mouse suggest that this gene plays an important role in cardiac muscle development.Alternate splicing of the gene results in ten transcript variants encoding different isoforms.Aberrant splice variants expressed in tumor cell lines have also been described.
Host:
Rabbit
Immunogen:
Recombinant protein of human BIN1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody