CASP3 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-13815-20UL
60 ul
£183.00
E-AB-13815-60UL
120 ul
£272.00
E-AB-13815-120UL
200 ul
£420.00
E-AB-13815-200UL
About this Product
- SKU:
- E-AB-13815
- Additional Names:
- A830040C14Rik;Apopain;CASP-3;CASP3;CC3;CPP-32;CPP32;CPP32B;Casp3a;Caspase 3;Caspase-3 subunit p12;Cysteine p;apoptosis-related cysteine peptidase;apoptosis-related cysteine protease;apoptosis-related cysteine protease a
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human CASP3
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-casp3_polyclonal_antibody-e_ab_13815
