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Antibodies

PNN Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-13517-20UL
60 ul
£183.00
E-AB-13517-60UL
120 ul
£272.00
E-AB-13517-120UL
200 ul
£420.00
E-AB-13517-200UL
About this Product
SKU:
E-AB-13517
Additional Names:
140 kDa nuclear and cell adhesion-related phosphoprotein,DRS,DRS protein,DRSP,Desmosome-associated protein,Domain-rich serine protein,MEMA,Melanoma metastasis clone A protein,Nuclear protein SDK3,PININ,PNN,Pinin,SR like protein,SR-like protein
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.2 mg/ml
Extra Details:
Pinin is a desmosomal associated protein involved with the maintenance of cell to cell adhesion of the epithelium. Pinin is a widespread protein and has been shown to play an important role in cell adhesion through its interaction with nuclear complexes. Pinin is also involved in pre-mRNA splicing through its interactions with a C-terminal RS domain of Cyclophilin G, a Moca type nuclear cyclophilin. Pinin becomes nuclear during the early stages of embryonic development and remains so throughout the entire period. Defects or lack of Pinin can be lethal at perinatal stages and causes defects in the cardiac outflow tract, axial skeleton, palate and dorsal dermis.
Host:
Rabbit
Immunogen:
Synthetic peptide of human PNN
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody