CERS4 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-13375-20UL
60 ul
£183.00
E-AB-13375-60UL
120 ul
£272.00
E-AB-13375-120UL
200 ul
£420.00
E-AB-13375-200UL
About this Product
- SKU:
- E-AB-13375
- Additional Names:
- 4,CerS4,FLJ12089,LAG1,LAG1 homolog ceramide synthase 4,LAG1 longevity assurance homolog 4,LASS 4,LASS4,LASS4 LAG1 homolog ceramide synthase 4,S. cerevisiae,TRAM homolog 1,Trh 1,Trh1,ceramide synthase 4,homolog of
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.9 mg/ml
- Extra Details:
- The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CERS4
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cers4_polyclonal_antibody-e_ab_13375
