HSD11B2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-13311-20UL
60 ul
£183.00
E-AB-13311-60UL
120 ul
£272.00
E-AB-13311-120UL
200 ul
£420.00
E-AB-13311-200UL
About this Product
- SKU:
- E-AB-13311
- Additional Names:
- 11 DH2,11 beta HSD2,11 beta hydroxysteroid dehydrogenase type 2,11-DH2,11-beta-HSD2,11-beta-hydroxysteroid dehydrogenase type 2,AME,AME1,Corticosteroid 11 beta dehydrogenase isozyme 2,Corticosteroid 11-beta-dehydrogenase isozyme 2,DHI2,HSD11B2,HSD11K,HSD2
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone.The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities.The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity.In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human HSD11B2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-hsd11b2_polyclonal_antibody-e_ab_13311
