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Antibodies

ZNF395 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-13288-20UL
60 ul
£183.00
E-AB-13288-60UL
120 ul
£272.00
E-AB-13288-120UL
200 ul
£420.00
E-AB-13288-200UL
About this Product
SKU:
E-AB-13288
Additional Names:
DKFZp434K1210,HD gene regulatory region binding protein 2,HD gene regulatory region-binding protein 2,HD-regulating factor 2,HDBP-2,HDBP2,HDRF-2,Huntington disease gene regulatory region-binding protein 2,Huntington's disease gene regulatory region bindin
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.8 mg/ml
Extra Details:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3'-CCGG-5' sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.
Host:
Rabbit
Immunogen:
Synthetic peptide of human ZNF395
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody