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Antibodies

CSTB Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-13179-20UL
60 ul
£183.00
E-AB-13179-60UL
120 ul
£272.00
E-AB-13179-120UL
200 ul
£420.00
E-AB-13179-200UL
About this Product
SKU:
E-AB-13179
Additional Names:
CHROW21,CPI B,CPI-B,CST 6,CST6,CSTB,CYTB,Cystatin B,Cystatin B (stefin B),Cystatin-B,EPM1,EPM1A,Liver thiol proteinase inhibitor,PME,STF B,STFB,Stefin-B,ULD
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.9 mg/ml
Extra Details:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Host:
Rabbit
Immunogen:
Synthetic peptide of human CSTB
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody