CYP2D6 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-13178-20UL
60 ul
£183.00
E-AB-13178-60UL
120 ul
£272.00
E-AB-13178-120UL
200 ul
£420.00
E-AB-13178-200UL
About this Product
- SKU:
- E-AB-13178
- Additional Names:
- CPD6,CYP2D,CYP2D6,CYP2D7AP,CYP2D7BP,CYP2D7P2,CYP2D8P2,CYP2DL1,CYPIID6,Cytochrome P450 DB1,Cytochrome P450 family 2 subfamily D member 6,Cytochrome P450 family 2 subfamily D polypeptide 6,Debrisoquine 4 hydroxylase,Flavoprotein linked monooxygenase,Microso
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug, sparteine and propafenone, both anti-arrythmic drugs, and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population, certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CYP2D6
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cyp2d6_polyclonal_antibody-e_ab_13178
