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Antibodies

PIK3R3 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-13018-20UL
60 ul
£183.00
E-AB-13018-60UL
120 ul
£272.00
E-AB-13018-120UL
200 ul
£420.00
E-AB-13018-200UL
About this Product
SKU:
E-AB-13018
Additional Names:
DKFZp686P05226,FLJ41892,OTTHUMP00000009783,OTTHUMP00000009786,P55G,Phosphatidylinositol 3 kinase,Phosphatidylinositol 3 kinase regulatory subunit gamma,Phosphatidylinositol 3 kinase regulatory subunit polypeptide 3,p55,p55 gamma,p55PIK,regulatory subunit
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.4 mg/ml
Extra Details:
Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3' position. PI 3-kinase p55 (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55 protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55 mRNAs are expressed in most human fetal and adult tissues, predominant expression is observed in the adult testis. Splice variant(s) of PI 3-kinase p55 have been identified, one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55 interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors.
Host:
Rabbit
Immunogen:
Synthetic peptide of human PIK3R3
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody