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Antibodies

UPF1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-13000-20UL
60 ul
£183.00
E-AB-13000-60UL
120 ul
£272.00
E-AB-13000-120UL
200 ul
£420.00
E-AB-13000-200UL
About this Product
SKU:
E-AB-13000
Additional Names:
ATP dependent helicase RENT1;ATP-dependent helicase RENT1;Delta helicase;FLJ43809;FLJ46894;HUPF 1;KIAA0221;NORF 1;NORF1;Nonsense mRNA reducing factor 1;RENT 1;RENT1;Regulator of nonsense transcripts 1;Smg 2;Smg 2 homolog nonsens;hUpf1;pNORF 1;pNORF1
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.1 mg/ml
Extra Details:
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in botHuman, MouseRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.
Host:
Rabbit
Immunogen:
Synthetic peptide of human UPF1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody