ARID1A Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12984-20UL
60 ul
£183.00
E-AB-12984-60UL
120 ul
£272.00
E-AB-12984-120UL
200 ul
£420.00
E-AB-12984-200UL
About this Product
- SKU:
- E-AB-12984
- Additional Names:
- ARI1A,ARID domain containing protein 1A,ARID domain-containing protein 1A,ARID1A,AT rich interactive domain 1A,AT rich interactive domain 1A (SWI like),AT rich interactive domain containing prote,actin-dependent regulator of chromatin subfamily F member 1
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin.It possesses at least two conserved domains that could be important for its function.First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus.Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation.It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ARID1A
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-arid1a_polyclonal_antibody-e_ab_12984
