ACO1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12938-20UL
60 ul
£183.00
E-AB-12938-60UL
120 ul
£272.00
E-AB-12938-120UL
200 ul
£420.00
E-AB-12938-200UL
About this Product
- SKU:
- E-AB-12938
- Additional Names:
- ACO 1,ACO1,ACOC,ACONS,Aconitase,Aconitase 1 soluble,Aconitase1,Aconitate hydratase,Citrate hydro lyase,Citrate hydro-lyase,Cytoplasmic aconitate hydratase,Ferritin repressor protein,IRE BP 1,IRE-BP 1,IREB 1,IREB1,IREBP,IREBP1,Iro,Iron regulatory protein 1
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ACO1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-aco1_polyclonal_antibody-e_ab_12938
