ABCA4 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12935-20UL
60 ul
£183.00
E-AB-12935-60UL
120 ul
£272.00
E-AB-12935-120UL
200 ul
£420.00
E-AB-12935-200UL
About this Product
- SKU:
- E-AB-12935
- Additional Names:
- ABC 10;ABC A4;ABC transporter;ABC10;ABCA 4;ABCA4;ABCR;ARMD 2;ARMD2;ATP binding cassette 10;ATP binding cassette sub family A member 4;ATP binding cassette sub family A member4;ATP binding cassette tr;ATP binding cassette transporter;abcA4;retinal-specific
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ABCA4
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-abca4_polyclonal_antibody-e_ab_12935
