FZD6 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12926-20UL
60 ul
£183.00
E-AB-12926-60UL
120 ul
£272.00
E-AB-12926-120UL
200 ul
£420.00
E-AB-12926-200UL
About this Product
- SKU:
- E-AB-12926
- Additional Names:
- FZD 6,FZD6,Frizzled 6 seven transmembrane spanning receptor,Frizzled drosophila homolog of 6,Frizzled family receptor 6,Frizzled homolog 6,Frizzled homolog 6 (Drosophila),Frizzled-6,Frizzled6,Fz 6,Fz-6,Fz6,Fzd6,Hfz 6,NDNC10,hFz6
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human FZD6
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-fzd6_polyclonal_antibody-e_ab_12926
