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Antibodies

PLAT Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-12879-20UL
60 ul
£183.00
E-AB-12879-60UL
120 ul
£272.00
E-AB-12879-120UL
200 ul
£420.00
E-AB-12879-200UL
About this Product
SKU:
E-AB-12879
Additional Names:
Alteplase,DKFZp686I03148,PLAT,Plasminogen activator tissue,Plasminogen activator tissue type,Reteplase,T Plasminogen Activator,T-plasminogen activator,Tissue plasminogen activator (t PA),Tissue type plasminogen activator,Tissue-type plasminogen,t PA,t-PA
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.4 mg/ml
Extra Details:
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Host:
Rabbit
Immunogen:
Synthetic peptide of human PLAT
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody