SLC22A17 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12870-20UL
60 ul
£183.00
E-AB-12870-60UL
120 ul
£272.00
E-AB-12870-120UL
200 ul
£420.00
E-AB-12870-200UL
About this Product
- SKU:
- E-AB-12870
- Additional Names:
- 24p3 receptor,24p3R,BOCT,BOIT,Brain type organic cation transporter,Brain-type organic cation transporter,Lipocalin-2 receptor,NGAL receptor,Neutrophil gelatinase associated lipocalin receptor,Neutrophil gelatinase-associated lipocalin receptor,Ngal,hBOIT
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.3 mg/ml
- Extra Details:
- Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human SLC22A17
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-slc22a17_polyclonal_antibody-e_ab_12870
