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Antibodies

NEB Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-12799-20UL
60 ul
£183.00
E-AB-12799-60UL
120 ul
£272.00
E-AB-12799-120UL
200 ul
£420.00
E-AB-12799-200UL
About this Product
SKU:
E-AB-12799
Additional Names:
DKFZp686C1456,FLJ11505,FLJ36536,FLJ39568,FLJ39584,NEB,NEB 177D,NEB177D,NEBU,NEM 2,NEM2,Nebulin
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.6 mg/ml
Extra Details:
This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue-, species-,and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin, the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy.
Host:
Rabbit
Immunogen:
Synthetic peptide of human NEB
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody