SMG8 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12757-20UL
60 ul
£183.00
E-AB-12757-60UL
120 ul
£272.00
E-AB-12757-120UL
200 ul
£420.00
E-AB-12757-200UL
About this Product
- SKU:
- E-AB-12757
- Additional Names:
- ABC 2,ABC2,Amplified in breast cancer gene 2 protein,Chromosome 17 open reading,FLJ10587,Protein smg 8 homolog,SMG8,SMG8 protein,chromosome 17 open reading frame 71,protein SMG8
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.3 mg/ml
- Extra Details:
- Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human SMG8
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-smg8_polyclonal_antibody-e_ab_12757
