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Antibodies

TRAF3 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-12665-20UL
60 ul
£183.00
E-AB-12665-60UL
120 ul
£272.00
E-AB-12665-120UL
200 ul
£420.00
E-AB-12665-200UL
About this Product
SKU:
E-AB-12665
Additional Names:
CAP 1,CAP-1,CAP1,CD40 associated protein 1,CD40 binding protein,CD40 bp,CD40 receptor associated factor 1,CD40 receptor-associated factor 1,CD40-binding protein,CD40BP,CRAF 1,CRAF1,IIAE5,LAP 1,LAP1,LMP1 associated protein,LMP1-associated protein 1,MIPT3,T
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.2 mg/ml
Extra Details:
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Host:
Rabbit
Immunogen:
Synthetic peptide of human TRAF3
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody