SOCS7 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12649-20UL
60 ul
£183.00
E-AB-12649-60UL
120 ul
£272.00
E-AB-12649-120UL
200 ul
£420.00
E-AB-12649-200UL
About this Product
- SKU:
- E-AB-12649
- Additional Names:
- Ash and phospholipase C gamma-binding protein,NAP 4,NAP 4 Fragment,NAP-4,NAP4,NCKAP4,Nck,Nck Ash and phospholipase C binding protein,Nck Ash and phospholipase C gamma binding protein,Nck associated protein 4,Nck-associated protein 4,SH2 domain containing
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.1 mg/ml
- Extra Details:
- The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human SOCS7
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-socs7_polyclonal_antibody-e_ab_12649
