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Antibodies

GEMIN2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-12645-20UL
60 ul
£183.00
E-AB-12645-60UL
120 ul
£272.00
E-AB-12645-120UL
200 ul
£420.00
E-AB-12645-200UL
About this Product
SKU:
E-AB-12645
Additional Names:
Component of gems 2,GEMI2,Gem (nuclear organelle) associated protein 2,Gem associated protein 2,Gemin-2,SIP 1,SIP-1,SIP1,SIP1 delta,SIP1-delta,SMN interacting protein 1,SMN interacting protein 1 delta,SMN-interacting protein 1,Survival interacting,gemin2
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.1 mg/ml
Extra Details:
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
Host:
Rabbit
Immunogen:
Synthetic peptide of human GEMIN2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody