RAD50 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12632-20UL
60 ul
£183.00
E-AB-12632-60UL
120 ul
£272.00
E-AB-12632-120UL
200 ul
£420.00
E-AB-12632-200UL
About this Product
- SKU:
- E-AB-12632
- Additional Names:
- DNA repair protein RAD50,Mrell,NBSLD,RAD50,RAD50 2,RAD50 PEN,RAD50 homolog,RAD50 homolog (S cerevisiae),RAD502,Rad 50,Rad50l,S. cerevisiae,Truncated RAD50 protein,hRAD50,homolog of,hsRAD50,rad50
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human RAD50
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-rad50_polyclonal_antibody-e_ab_12632
