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Antibodies

PFN2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-12624-20UL
60 ul
£183.00
E-AB-12624-60UL
120 ul
£272.00
E-AB-12624-120UL
200 ul
£420.00
E-AB-12624-200UL
About this Product
SKU:
E-AB-12624
Additional Names:
D3S1319E,PFL,PFN 2,PROF2,Pfn2,Profilin II,Profilin-2,Profilin2,ProfilinII
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.3 mg/ml
Extra Details:
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Host:
Rabbit
Immunogen:
Synthetic peptide of human PFN2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody