CHRNA7 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12583-20UL
60 ul
£183.00
E-AB-12583-60UL
120 ul
£272.00
E-AB-12583-120UL
200 ul
£420.00
E-AB-12583-200UL
About this Product
- SKU:
- E-AB-12583
- Additional Names:
- 7nAChR,ACHA7,AChR,Acra7,a7 nicotinic acetylcholine receptor,acetylcholine receptor,alpha 7 neuronal nicotinic acetylcholine receptor,alpha-7 nicotinic cholinergic receptor subunit,alpha-7 subunit,alpha7,cholinergic receptor,neuronal nic,neuronal nicotinic
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.3 mg/ml
- Extra Details:
- The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CHRFAM7A
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-chrna7_polyclonal_antibody-e_ab_12583
