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Antibodies

MMP11 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-12573-20UL
60 ul
£183.00
E-AB-12573-60UL
120 ul
£272.00
E-AB-12573-120UL
200 ul
£420.00
E-AB-12573-200UL
About this Product
SKU:
E-AB-12573
Additional Names:
MMP-11,MMP11,Matrix Metalloproteinase 11,Matrix metalloproteinase-11,Mmp11,SL 3,SL-3,SL3,ST3,STMY3,Stromelysin 3,Stromelysin III,Stromelysin-3
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.4 mg/ml
Extra Details:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
Host:
Rabbit
Immunogen:
Synthetic peptide of human MMP11
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody