GSK3 alpha Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12494-20UL
60 ul
£183.00
E-AB-12494-60UL
120 ul
£272.00
E-AB-12494-120UL
200 ul
£420.00
E-AB-12494-200UL
About this Product
- SKU:
- E-AB-12494
- Additional Names:
- DKFZp686D0638,GSK 3 alpha,GSK 3A,GSK-3 alpha,GSK3A,GSK3alpha,Glycogen synthase kinase 3 alpha,Glycogen synthase kinase-3 alpha,Gsk3a,Serine/threonine protein kinase GSK3A
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human GSK3A
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-gsk3_alpha_polyclonal_antibody-e_ab_12494
