GRPR Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12444-20UL
60 ul
£183.00
E-AB-12444-60UL
120 ul
£272.00
E-AB-12444-120UL
200 ul
£420.00
E-AB-12444-200UL
About this Product
- SKU:
- E-AB-12444
- Additional Names:
- BB2,Bombesin BB2 receptor,GRP R,GRP preferring bombesin receptor,GRP-R,GRP-preferring bombesin receptor,GRPR,Gastrin Releasing Peptide Receptor,Gastrin-releasing peptide receptor,Grp/bombesin receptor,Grpr,bombesin receptor 2
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.1 mg/ml
- Extra Details:
- Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human GRPR
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-grpr_polyclonal_antibody-e_ab_12444
