Fibulin 5 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12408-20UL
60 ul
£183.00
E-AB-12408-60UL
120 ul
£272.00
E-AB-12408-120UL
200 ul
£420.00
E-AB-12408-200UL
About this Product
- SKU:
- E-AB-12408
- Additional Names:
- ADCL2,ARCL1A,ARMD3,Dance,Developmental arteries and neural crest EGF like protein,Developmental arteries and neural crest EGF-like protein,EVEC,FBLN5,FIBL 5,FIBL-5,FLJ90059,Fbln5,Fibulin-5,UP50,Urine p50 protein
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.2 mg/ml
- Extra Details:
- The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human FBLN5
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-fibulin_5_polyclonal_antibody-e_ab_12408
