E2F4 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12375-20UL
60 ul
£183.00
E-AB-12375-60UL
120 ul
£272.00
E-AB-12375-120UL
200 ul
£420.00
E-AB-12375-200UL
About this Product
- SKU:
- E-AB-12375
- Additional Names:
- E2F 4,E2F transcription factor 4,E2F transcription factor 4 p107/p130 binding,E2F-4,E2F4,Transcription factor E2F 4,Transcription factor E2F4,p107/p130 binding protein
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human E2F4
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-e2f4_polyclonal_antibody-e_ab_12375
