DSP Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-12373-20UL
60 ul
£183.00
E-AB-12373-60UL
120 ul
£272.00
E-AB-12373-120UL
200 ul
£420.00
E-AB-12373-200UL
About this Product
- SKU:
- E-AB-12373
- Additional Names:
- 250/210 kDa paraneoplastic pemphigus antigen;DCWHKTA;DESP;DP;DP I;DP II;DPI;DPII;DSP;Desmoplakin;Desmoplakin (DPI DPII);Desmoplakin I;Desmoplakin II;KPPS2;PPKS 2;PPKS2
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human DSP
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-dsp_polyclonal_antibody-e_ab_12373
