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Antibodies

BDNF Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-12290-20UL
60 ul
£183.00
E-AB-12290-60UL
120 ul
£272.00
E-AB-12290-120UL
200 ul
£420.00
E-AB-12290-200UL
About this Product
SKU:
E-AB-12290
Additional Names:
ANON2,Abrineurin,BDNF,BULN2,Brain Derived Neurotrophic Factor,Brain-derived neurotrophic factor,MGC34632,Neurotrophin
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.3 mg/ml
Extra Details:
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
Host:
Rabbit
Immunogen:
Synthetic peptide of human BDNF
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody