PLEKHG6 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-11416-20UL
60 ul
£183.00
E-AB-11416-60UL
120 ul
£272.00
E-AB-11416-120UL
200 ul
£420.00
E-AB-11416-200UL
About this Product
- SKU:
- E-AB-11416
- Additional Names:
- FLJ10665,MGC126315,MGC126353,MGC126354,Myosin interacting guanine nucleotide exchange factor,PH domain containing family G member 6,Pleckstrin homology domain containing family G (with RhoGef domain) member 6,Pleckstrin homology domain-containing family G
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human PLEKHG6
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-plekhg6_polyclonal_antibody-e_ab_11416
