MRE11 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-11403-20UL
60 ul
£183.00
E-AB-11403-60UL
120 ul
£272.00
E-AB-11403-120UL
200 ul
£420.00
E-AB-11403-200UL
About this Product
- SKU:
- E-AB-11403
- Additional Names:
- AT like disease,ATLD,Ataxia telangiectasia disorder like,DNA recombination and repair protein,Double strand break repair protein MRE11A,Double-strand break repair protein MRE11A,HNGS1,endo/exonuclease Mre11,meiotic recombination (S. cerevisiae) 11 homolog
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human MRE11A
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-mre11_polyclonal_antibody-e_ab_11403
