KIF1C Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-11350-20UL
60 ul
£183.00
E-AB-11350-60UL
120 ul
£272.00
E-AB-11350-120UL
200 ul
£420.00
E-AB-11350-200UL
About this Product
- SKU:
- E-AB-11350
- Additional Names:
- KIF1C;Kif1c;Kinesin family member 1C;Kinesin-like protein KIF1C;LTXS1
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell . Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis . KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons . Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein with abundant expression in heart and skeletal muscle . Tyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C is capable of forming homodimers and can noncovalently associate with 14-3-3 beta, gamma, epsilon and zeta . In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human KIF1C
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-kif1c_polyclonal_antibody-e_ab_11350
