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Antibodies

HYAL2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-11315-20UL
60 ul
£183.00
E-AB-11315-60UL
120 ul
£272.00
E-AB-11315-120UL
200 ul
£420.00
E-AB-11315-200UL
About this Product
SKU:
E-AB-11315
Additional Names:
HYAL2,Hyal 2,Hyal-2,Hyal2,Hyaluronidase 2,Hyaluronidase 2 Precursor,Hyaluronidase-2,Hyaluronoglucosaminidase 2,Hyaluronoglucosaminidase-2,LUCA 2,LUCA-2,LUCA2,Lung carcinoma protein 2,PH 20 homolog,PH-20 homolog,PH20 homolog,lysosomal hyaluronidase
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.6 mg/ml
Extra Details:
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
Host:
Rabbit
Immunogen:
Recombinant protein of human HYAL2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody