HSP40-4 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-11313-20UL
60 ul
£183.00
E-AB-11313-60UL
120 ul
£272.00
E-AB-11313-120UL
200 ul
£420.00
E-AB-11313-200UL
About this Product
- SKU:
- E-AB-11313
- Additional Names:
- DJ 2,DJ2,DNAJ2,DNJA1,DjA1,DnaJ (Hsp40) homolog,DnaJ homolog subfamily A member 1,DnaJ protein homolog 2,Dnaja1,HDJ-2,HDJ2,HSDJ,HSJ-2,HSJ2,HSPF4,Heat shock 40 kDa protein 4,Heat shock protein J2,Hum,hDJ 2,heat shock protein DNAJ like 2,member 1,subfamily A
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human DNAJA1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-hsp40_4_polyclonal_antibody-e_ab_11313
