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Antibodies

HIF1 alpha Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-11289-20UL
60 ul
£183.00
E-AB-11289-60UL
120 ul
£272.00
E-AB-11289-120UL
200 ul
£420.00
E-AB-11289-200UL
About this Product
SKU:
E-AB-11289
Additional Names:
ARNT interacting protein,ARNT-interacting protein,Basic helix loop helix PAS protein MOP1,Basic-helix-loop-helix-PAS protein MOP1,Class E basic helix-loop-helix protein 78,HIF 1A,HIF 1alpha,HIF-1-alpha,HIF1,HIF1 A,HIF1 Alpha,HIF1-alpha,HIF1A,bHLHe78
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.6 mg/ml
Extra Details:
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human HIF1A
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody