FAM3B Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-11214-20UL
60 ul
£183.00
E-AB-11214-60UL
120 ul
£272.00
E-AB-11214-120UL
200 ul
£420.00
E-AB-11214-200UL
About this Product
- SKU:
- E-AB-11214
- Additional Names:
- 2-21;C21orf11;C21orf76;Cytokine like protein 2 21;Cytokine-like protein 2-21;FAM3B;Fam3b;Family with sequence similarity 3 member B;ORF9;PANDER;PRED44;Pancreatic-derived factor;Protein FAM3B
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.7 mg/ml
- Extra Details:
- FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human FAM3B
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-fam3b_polyclonal_antibody-e_ab_11214
